🧠 Cornell Notes: Psychopathology

Cues / Prompts

  • What is OCD?
  • What is the biological explanation of OCD?
  • What are COMT and SERT genes?
  • What part of the brain is involved in OCD?
  • What research supports the genetic explanation?
  • AO3: Strengths of biological explanation?
  • AO3: Weaknesses of biological explanation?

Notes

OCD is an anxiety disorder characterized by repetitive thoughts (obsessions) and behaviours (compulsions).

The biological explanation includes genetic and neural components. Genes may create a vulnerability; abnormalities in neurotransmitters and brain structure are implicated.

COMT gene affects dopamine levels; SERT gene impacts serotonin — both associated with OCD symptoms.

The Orbitofrontal Cortex (OFC) is overactive in OCD, linked to decision-making and worry.

Nestadt et al. (2010): 68% concordance in MZ twins vs. 31% in DZ twins for OCD.

Strengths (AO3): Supported by empirical evidence like brain scans and twin studies. High scientific credibility.

Weaknesses (AO3): Reductionist — ignores environment. Gene expression doesn't always result in disorder. Suggests gene-environment interaction.

Summary

I understand how OCD can be explained biologically using genes and brain structure. COMT/SERT and OFC are key elements. Still need to practice applying AO3 to 16-mark questions and add more studies like Nestadt.

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